Download e-book for iPad: Antiviral Methods and Protocols (Methods in Molecular by Derek Kinchington, Raymond F. Schinazi

By Derek Kinchington, Raymond F. Schinazi

ISBN-10: 0585235686

ISBN-13: 9780585235684

ISBN-10: 0896035611

ISBN-13: 9780896035614

Skilled scientists describe-in an easily-followed format-their cutting-edge suggestions for comparing antiviral compounds. The assays defined comprise structures for investigating medicines used opposed to herpesviruses, hepatitis viruses, human immunodeficiency viruses, human papillomaviruses, and influenza viruses. those well-tested tools diversity from mobile assays to a couple of the main updated molecular techniques for picking out compounds which are energetic opposed to viral enzymes and the improvement of viral resistance opposed to medicines at the moment in use. well timed and complete, Antiviral tools and Protocols deals trendy researchers in academia, medical departments, and the pharmaceutical the strong, reproducible, and novel tools had to assessment compounds potent opposed to either acute and persistent infections.

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Additional resources for Antiviral Methods and Protocols (Methods in Molecular Medicine)

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L. (1994) Ann. Rep. Med. Chem. 26, 123132. 10. Kohlstaedt, L. , Friedman, J. , Rice, P. , and Steitz, T. A. 5 angstroms resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256, 17831790. 11. , and Adams, J. (1993) Preliminary structural analysis of the mutations selected by non-nucleoside inhibitors of HIV-1 reverse transcriptase. Biorg. Med. Chem. Lett. 3, 721726. 12. , et al. (1995) High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Nature Struct.

Clinical Applications of PCR, edited by Y. M. Dennis Lo, 1998 15. Molecular Bacteriology: Protocols and Clinical Applications, edited by Neil Woodford and Alan Johnson, 1998 14. Tumor Marker Protocols, edited by Margaret Hanausek and Zbigniew Walaszek, 1998 13. Molecular Diagnosis of Infectious Diseases, edited by Udo Reischl, 1998 12. Diagnostic Virology Protocols, edited by John R. Stephenson and Alan Warnes, 1998 11. Therapeutic Application of Ribozymes, edited by Kevin J. Scanlon, 1998 10. Herpes Simplex Virus Protocols, edited by S.

Effective treatment and preventive measures are not usually available. 5 Biosafety/Laboratory Containment Level Criteria The hazard of a virus and/or the risks associated with its use in particular laboratory procedures determine the appropriate level of containment. Most classifications are designated in ascending order and include four kinds of laboratories: US Department of Health and Human Services (USDHHS) and the Page 17 Table 4 Classification of Viruses on the Basis of Hazard or Risk as Adopted in the European Community (EC), the United Kingdom (UK) and the United States (US)VirusECUKUSDengue viruses types 14332Ebola virus444Hantaan (Korean hemorrhagic fever) virus333Hepatitis A virus222Hepatitis B virus332Hepatitis C virus332Hepatitis D virus332Hepatitis E virus332Herpesvirus simiae333Human herpes viruses 18222Human immunodeficiency viruses332Human papilloma viruses222Human T-cell lymphotropic viruses I and II332Influenza types A, B, and C222Japanese encephalitis virus333Lassa virus444Marburg virus444Measles virus222Mumps virus222Monkeypox virus332Rabies virus332Vaccinia virus222Variola (smallpox) virus444Venezuelan equine encephalitis virus333 World Health Organization (WHO) identify Biosafety Levels 1, 2, 3, and 4 and in the United Kingdom the Advisory Committee on Dangerous Pathogens (ACDP) categorizes Laboratory Containment Levels 1, 2, 3, and 4 (46).

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Antiviral Methods and Protocols (Methods in Molecular Medicine) by Derek Kinchington, Raymond F. Schinazi

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Download e-book for iPad: Antiviral Methods and Protocols (Methods in Molecular by Derek Kinchington, Raymond F. Schinazi
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