New PDF release: Antithrombotic Drug Therapy in Cardiovascular Disease

By Edward F. Plow PHD, Peter Kelly MD (auth.), Arman T. Askari, A. Michael Lincoff (eds.)

ISBN-10: 1603272348

ISBN-13: 9781603272346

Substantial morbidity and mortality is still linked to thrombotic occasions has prompted the swift growth of the to be had armamentarium to strive against pathologic thrombosis. Pathologic thrombosis performs an important function within the pathogenesis of acute coronary syndromes (ACS), ischemic issues of percutaneous coronary intervention (PCI), venous thromboembolic illness, and embolic problems of arrhythmias and numerous cardiomyopathies. Written by way of specialists within the box, Antithrombotic Drug remedy in Cardiovascular Disease conscientiously examines person and numerous combos of the on hand antithrombotic regimens together with fibrinolytic brokers, antiplatelet remedies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticogulant remedies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and artificial issue X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). an in depth review, Antithrombotic Drug remedy in Cardiovascular Disease provides the proof demonstrating the efficacy of accessible antithrombotic remedies in particular ailment states equivalent to atrial traumatic inflammation, cardiomyopathy, valvular center illness, and heparin-induced thrombocytopenia (HIT).

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Extra resources for Antithrombotic Drug Therapy in Cardiovascular Disease

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Thromb Haemost 82:601–609 111. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM (1996) A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698–3703 112. Heit JA (2006) Epidemiology of venous thromboembolism. In: Colman RW, Marder VJ, Clowes AW, George JN, Goldhaber SZ (eds) Hemostasis and thrombosis. Basic principles and clinical practice, 5th edn. Lippincott Williams and Wilkins, Philadelphia, PA, pp 1227–1233 113.

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Haemostasis 23:183–193 69. Ye J, Esmon NL, Esmon CT, Johnson AE (1991) The active site of thrombin is altered upon binding to thrombomodulin: two distinct structural changes are detected by fluorescence, but only one correlates with protein C activation. J Biol Chem 266:23016–23021 70. Taylor FB Jr, Peer GT, Lockhart MS, Ferrell G, Esmon CT (2001) Endothelial cell protein C receptor plays an important role in protein C activation in vivo. Blood 97:1685–1688 71. Bajzar L, Morser J, Nesheim M (1996) TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascade through the thrombin-thrombomodulin complex.

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Antithrombotic Drug Therapy in Cardiovascular Disease by Edward F. Plow PHD, Peter Kelly MD (auth.), Arman T. Askari, A. Michael Lincoff (eds.)


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