Celso Pereira's Allergic diseases - highlights in the clinic, mechanisms and PDF

By Celso Pereira

ISBN-10: 9535102273

ISBN-13: 9789535102274

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Extra info for Allergic diseases - highlights in the clinic, mechanisms and treatment

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This complexity is reflect of the large number of new genes (and new splice variants and the expanding classes of noncoding RNAs) discovered by the ongoing sequencing of genomes and transcripts. Complicating this is the lack of information on molecular interactions; genes expression can only measure gene transcription, not translation, and certainly not the complex regulatory pathways and interactions leading to the array result, a snapshot of one sample at one moment. This leads to the current state of gene expression microarray data in asthma/allergy, where although many differentially expressed genes have been found and verify potential biomarkers and/or therapeutic targets are still being validated, evaluated and explored with no clinical diagnostic or therapeutic benefit to date.

Toxicol. Sci. 36: 395-401, ISSN 0388-1350. , & Ueno K. (2011). Lower expression of histamine H(4) receptor in synovial tissues from patients with rheumatoid arthritis compared to those with osteoarthritis. Rheumatol Int. , & Ueno K. (2011). Increased expression of the histamine H4 receptor subtype in hypertrophic differentiation of chondrogenic ATDC5 cells. J Cell Biochem. In press, ISSN 1097-4644. 3 The Type I and Type II Receptor Complexes for IL-4 and IL-13 Differentially Regulate Allergic Lung Inflammation Nicola M.

Zandieh, A. & Zhu, X. (2001) The sequence of the human genome. 1304-1351, IISN 0036-8075. Vercelli, D. (2008). Discovering susceptiblility genes for asthma and allergy. Nat Rev Immunol, Vol. 3, pp169-182. Vercelli, D. a (2010). Genetics and biology of asthma 2010: La´ci darem la mano. J Allergy Clin Immunol, Vol 125, pp347-348. Vercelli, D. b (2010). Gene-environment interactions in asthma and allergy : the end of the beginning?. Curr Opin Allergy Immunol, Vol. 145-148, IISN 15284050. ; Taioli, E.

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Allergic diseases - highlights in the clinic, mechanisms and treatment by Celso Pereira


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